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KMID : 0363320210420030385
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Journal of Korean Oriental Internal Medicine
2021 Volume.42 No. 3 p.385 ~ p.402
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The Effect of Banhasasim-tang in Cough: A Systematic Review and Meta-analysis
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Han Seung-Hee
Sun Seung-Ho
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Abstract
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Objective: This study confirms the safety and efficacy of Banhasasim-tang (BST) against cough through systematic review and meta-analysis.
Methods: PubMed, Cochrane, ScienceDirect, Wiley online library, OASIS, KISS, NDSL, RISS, Science and Technology Society Village, DBpia, CNKI, J-STAGE, and CiNii were used as search engines. The search period was from the start of search engine support to June 30. 2020. And search language was not limited. Cochrane’s risk of bias (RoB) tool was used to evaluate the quality of the studies. A meta-analysis of the total effective rate (TER), cough symptom score, and spirometry results was performed using the Review Manager program.
Results: 6 studies were finally selected. The group using BST showed significant symptom relief, as the odds ratio (OR) value of TER was 5.56 times higher (95% CI: 3.50, 8.82, P<0.0001) compared to the control groups. The reported adverse effects did not occur in the intervention group. In addition, the cough symptom score and spirometry results showed that BST was more effective than Western medicine alone.
Conclusion: BST can be expected to relieve cough, and it can be applied to chronic cough that is not treated with existing treatments. However, due to the low quality of the selected articles, additional high-quality RCTs will be required in the future.
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KEYWORD
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Banhasasim-tang, cough, systematic review, meta-analysis
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